A Pandemic known as the living death cripples civilization. A small group of surviving scientists and doctors — located in Atlanta, Georgia (U.S. state), home of the Centers for Disease Control and Prevention — work on a cure to save what remains of humanity. To complete their work they need information stored on a computer system in New York City. Pearl Prophet volunteers for the dangerous courier mission and is made into a cyborg through surgical augmentation.
In the year 2074, the cybernetics market is dominated by two rival companies: USA's Pinwheel Robotics and Japan's Kobayashi Electronics. ‘Cyborgs’ are commonplace, used for anything from soldiers to prostitutes. Casella "Cash" Reese (Angelina Jolie) is a Pinwheel prototype cyborg developed for corporate espionage and assassination. She is filled with a liquid explosive called "Glass Shadow". Pinwheel's CEO, Martin Dunn (Allan Garfield), plans to eliminate the entire Kobayashi board of directors using Cash as a suicide bomber to precipitate a hostile takeover of the company and obtain a monopoly over the cyborg market.
The film is set in a desolate post apocalyptic world where a once thriving age of man and cyborgs has come to an end. Cyborgs are now hunted for their parts. Cash (Haje), a female cyborg learns from Doc Edford (Margaret Avery) that she is somehow pregnant.