A lucky few survive a disaster. But what if Death has a design? Can you escape Death or will it deliver you to your Final Destination?
After narrowly avoiding a fatal plane explosion, a group of seemingly lucky teen classmates finds that Death is not so easily cheated.
When Kimberly has a violent premonition of a highway pileup she blocks the freeway, keeping a few others meant to die, safe. Or are they? The survivors mysteriously start dying and it's up to Kimberly to stop it before she's next.
High-school student Wendy Christensen visits an amusement park for a McKinley High senior-class field trip, along with her boyfriend Jason Wise, her best friend Carrie Dreyer, and Carrie's boyfriend Kevin Fischer. As they board the Devil's Flight roller-coaster, Wendy has a premonition that the hydraulics securing the seat belts and coaster cars will fail during the ride, killing everyone on board. She panics and a fight breaks out, and several people leave or are forced off the ride including Kevin, best friends Ashley Freund and Ashlyn Halperin, alumnus Frankie Cheeks, athlete Lewis Romero and goth couple - Ian McKinley and Erin Ulmer. Moments later the roller-coaster derails and kills the remaining passengers, leaving Wendy devastated.
College student Nick O'Bannon visits the McKinley Speedway with his girlfriend Lori Milligan and their friends Hunt Wynorski and Janet Cunningham. While watching the race, Nick has a premonition of a horrible car accident that sends debris into the stands, causing the stadium to collapse. When Nick panics, a fight breaks out and several people leave the stadium, including Lori, Hunt, Janet, security guard George Lanter, mechanic Andy Kewzer, his girlfriend Nadia Monroy, racist tow truck driver Carter Daniels, and mother Samantha Lane. As Nadia berates the group, a stray tire flies out of the stadium and decapitates her.
A premonition helps Sam and his colleagues escape a fatal accident. Death, however, is not quite ready to part with its victims and decides to come after them.