After noticing that Mikan has been acting strangely around Junko, Ryota is shocked to discover a video of the student council's killing game. Junko reveals that she plans to combine this video with Ryota's anime to create something that will brainwash people and send them into despair, threatening to subject his classmates to another killing game should he refuse to cooperate. Meanwhile, as Kyosuke arrives to help deal with the Reserve Course riots, Nagito, who has returned from his long absence, mentions that he has seen Mikan on the school grounds, prompting the rest of the class to go off in search for her. During their search, Nagito leads Chiaki to the secret room where Junko and Ryota are, having swordswoman Peko Pekoyama hold off Mukuro. Nagito attempts to shoot Junko but is stopped by Izuru, who Chiaki recognises as Hajime, while Ryota escapes and runs into Chisa, who rushes towards the scene.
「希望ヶ峰学園史上最大最悪の事件」や予備学科によるパレードにより、希望ヶ峰学園は混乱していく。また、七海たちのクラスでは罪木が謎の失踪を遂げる。クラスメイトの危機にいてもたってもいられない一同は、危険を顧みず捜索に向かった。そのとき、江ノ島は運命の出会いを果たした御手洗に、自分の計画の全貌を語っていた。
Chisa aparece para confrontar a Junko, quien revela su plan de lavarle el cerebro a su clase en Ultimate Despairs, mostrando su efectividad al hacer que un estudiante se mate a sí mismo por orden. Mientras tanto, Chiaki escapa con Nagito e informa al resto de la clase, quienes deciden ir a ayudar a su maestra.
Junko ha rivelato il marcio dell'accademia Picco della Speranza e ora un'orda di studenti inferociti sta protestando davanti ai cancelli della scuola.
Après avoir remarqué que Mikan se comportait bizarrement avec Junko, Ryōta est choqué de découvrir une vidéo du jeu de massacre du conseil des élèves. Junko révèle qu'elle a l'intention de combiner cette vidéo avec l'anime de Ryōta pour créer quelque chose qui lavera le cerveau des gens et les plongera dans le désespoir, menaçant de soumettre ses camarades de classe à un autre jeu de massacre s'il refuse de coopérer.
