Diego moves next door to Jesse Warner and her family, and asks her out.
Jesse's movie date with Diego ends up in the emergency room when she gets a piece of candy stuck in her nose.
Jesse's been taking it real slow in her relationship with Diego, but things begin heating up and she may not wish to cool them off.
Jesse learns that Diego once had a relationship with the nude model he's been painting at his house.
On the eve of Halloween, Jesse gets quite a scare---her ex shows up after seven years and wants to be back in Little John's life.
Jesse's brush with an art-gallery owner may cost Diego a chance to show his work.
Jesse's ex-husband surprises her with a kiss, just after she and Diego have a spat.
Jesse invites Diego to Thanksgiving dinner, even though her ex will be in attendance.
Little John is in a school play, Darren is in a commercial and Diego goes to great lengths to try to prove to Jesse that Roy is a jerk but Jesse won't listen.
Diego decides that if Jesse wants Roy he won't stand in the way. So he goes to Roy's to tell him, but he catches Roy with another woman. He tries to tell Jesse but she won't listen, that is until Junior finally speaks and tells her it's true. She throws Roy out.
Diego and Jesse pretend to be husband and wife while shopping for a car. Also now that Junior talks, he and Darren try and pick up girls.
Jesse decides to go back to high school. Her teacher asks her out and she doesn't know if she should say yes because he's her teacher. She finally decides to go out with him but finds out that he's a weirdo so she dumps him. Diego dates a student.
Jesse, Linda and Carrie go to the wedding of a former high school classmate and Jesse is asked to be the maid of honor because the bride's sister couldn't make it. Jesse agrees. Linda makes out with a guy in the coat checkroom only to find out later that he's the groom. Jesse goes to talk to him to set him straight but the bride walks in as Jesse is giving him a hug and she thinks that Jesse is the one that was making out with him. When Jesse tries to cover for Linda, Linda says that it was actually her that made out with him. Then practically every woman in the room says that they also made out with him.
Although they have split up, Jesse turns up for a date with Diego that they arranged long before, only to find him about to go out with his new girlfriend. Jesse deals with it by acting it out her fantasies of a forties film noir.
Diego feels that Gwen is becoming increasingly clingy, but Jesse thinks she is just being nice, until Gwen transforms herself into a Jesse look-alike. John Warner Sr. dates an old friend, Mary Anne that he meets up with after thirty years.
John Warner Sr. decides to go off to Alaska to climb Mt McKinley with Mary Anne, leaving the bar to the care of his three children. When they fail to sell it, they have to decide between them how to fit in running it with the other things that they want to do in their lives.
Darren suggests a Charlie's Angels theme for the bar. Diego invites Jesse round to dinner, but it is a disaster, capped by her being so fearful that things won't work out well between them that it ruins what is left of the evening. It takes Diego some time to convince her that things could work out better.
When Jesse writes a love letter to Diego she never plans to send and little John sends it she tries to retrieve it. But she angered the mailman because he doesn't put the mail in the right mail slots and now to anger her he refuses to give her the letter she wrote to Diego because it's addressed to him not her. She then tries to put her arm in the mail slot and retrieve it but she gets stuck.
Diego's parents come to Buffalo and Jesse has to go pick them up at the airport but she picks up the wrong Vasquez's. When she goes with Diego to pick up the right Vasquez's they don't seem as happy to see Jesse as the wrong ones were.
Another kid is beating up Little John at school so Jesse goes to talk to his mother. His mother is actually his stepmother and her mother. Jesse now has a stepbrother and Little John has an uncle his own age. She asks Jesse to borrow five grand because her relationship with her new husband, Fez Foose a member of the rock band ""The Ass Police"" isn't going so well. Jesse can only come up with 1200,65$ and her mother takes the money and runs out on her again to go to South America. Jesse goes to confront her mother on the plane and her mother decides to stay.
While on a scavenger hunt Jesse and Diego find a baby in the park. Jesse wants to keep it but Diego and her family tell her it's not a good idea. Just as Diego starts to like the baby the mother is found and the baby returned.
Jesse gets a full scholarship for nursing school. Diego faces deportation when his visa runs out. He gets a job at UCLA which is California but Jesse doesn't want him to take it because it's so far away from her but he doesn't have a choice. Jesse goes to talk to him and to her surprise he asks her to marry him. To be continued...
Jesse tells Diego she can't marry him. Then we go forward four months and Jesse gets a job as a nurse's aid but quits when she can't handle it. She does however get it back later. Diego returns having quit his job at UCLA because he got his old job back since funding was given for the art department. He surprises Jesse by popping the question again but she still says no.
Jesse joins a car pool but Little John's red ants infest the car so she gets a ride back with Diego. Linda won't leave Diego's place.
A flu epidemic breaks out at the center where Jesse works. Carrie gets mad at Jesse for calling a monkey at the zoo stupid. Linda fears that Little John is becoming a geek.
Jesse's plans for a little barbecue are shot to hell when more people than are invited show up.
Kurt starts a rumor that Jesse is a thief. Linda thinks that Diego is in love with her after he accidentally sees her naked.
Jesse and Diego's relationship is fired up again while trying to change a flat tire on Jesse's car.
Jesse tries to win Diego back and gather up the nerve to ask him to marry her.
Dr. Danny and Carrie go out on a date and Jesse tags along when she finds out that Diego and Irma where once engaged but she left him at the altar.
Jesse has a Christmas party.
Jesse revives a squirrel and then it runs rampant; however, when they find it's dead. Diego has a snow fight with Little John and his friends.
Diego gets passed up for a teaching position so Irma takes him to Niagara Falls to cheer him up but scares him off. She tells him she's going to change into something more comfortable but comes out in a wedding dress and proposes to him. That leads Diego to go back to Buffalo and apologize to Jesse for having proposed to her when he came back to Buffalo from California. He now knows how it feels to get asked out of the blue to marry someone. Jesse and Diego get back together but hold off on getting married. Kurt slips a disk in his spine while trying to lift a heavy box at work. At the hospital Jesse gets asked out by the attending doctor but passes on his offer when Diego shows up and wants to get back together. Dr. Danny feels uncomfortable around the attending doctor.
When Jesse's car is stolen she goes looking for a new used car. Linda's mechanic gets her a good deal on an '84 Volvo so she takes it but while out driving it with Diego she notices her old car in an alley. She reports that she found it and when she shows a uniformed officer its location it isn't there anymore. While out driving again though they notice it again at a different location but it gets destroyed.
Linda doesn't want to go to her high school reunion because she doesn't feel she's accomplished anything since graduating.
Jesse recounts the events leading to the birth of Little John when Diego tells her he wants a big family.
Diego returns from Chile with a moustache and decides to shave it off when Jesse asks him but changes his mind when Dr. Danny tells him he's whipped. Linda gets a job as a campus security guard and takes her job too seriously.
Jesse earns a blue jacket at work. She wanted it because nobody believes she works there. Diego accidentally sets his house on fire but thinks it was Linda's fault because of the mess she refuses to clean up in the kitchen.
Diego has the winter blahs and Jesse tries to cheer him up by buying tickets for them to Bermuda but Diego's passport was hidden in his old fridge and that was sent to the dump. They head to the dump to try to find but have no luck so Jesse gives the tickets to Danny and Carrie.
Little John accidentally sees Jesse naked when Diego spends the night and Carrie challenges Linda to a boxing match.
Kurt tries to teach Jesse to be a phlebotomist, Diego doesn't get his professorship and he has to share his studio with a British guy who's really rude and doesn't respect his space. Diego gets fired for smashing a nude painting of Jesse over Dawson's (the British guy) head.
Facing deportation again Diego marries Linda because Jesse didn't want to but then she changes her mind but it's too late.