Mark Lawson talks to comedian, writer and actress Jo Brand. After a decade working as a psychiatric nurse, Jo turned her hand to comedy in the 1980s and has spent nearly 30 years at the top of what is widely accepted to be a male-dominated genre, receiving recognition by BAFTA in 2011 for her performance in the sitcom Getting On. One of the most important female comics of her generation, she reveals the backlash she faced on her arrival on the alternative comedy scene, her approach to hecklers and taboos, as well as her experiences as a TV personality - from the pressure of having her own sketch show, Jo Brand: Through The Cakehole, to being on panel shows such as Have I Got News for You and Mock the Week.