A British hitman living in LA is poisoned with the Beijing Cocktail which blocks the adrenal gland. To survive he must keep a constant flow of adrenalin coursing through his body while finding the cure and his would-be killers.
Chev Chelios, an English people hitman based in Los Angeles, works for a crime syndicate led by Don "Carlito" Carlos. Chelios is contracted by Carlito to kill mafia boss Don Kim as members of the Triad (organized crime) have been encroaching on Carlito's business. Chelios goes to Don Kim and apparently murders him.
Chev Chelios (Jason Statham) lands in the middle of an intersection after Crank (film) He is scooped off the street by gangsters and removed from the scene. Chev wakes up in a makeshift hospital and sees doctors removing his heart while Johnny Vang (Art Hsu) watches. The doctors place an artificial heart in his chest. He wakes up later and escapes, noticing an external battery pack is attached to him. After interrogating a thug, he learns the location of Johnny Vang: the Cypress Social Club.
