A brother and sister driving home through an isolated countryside from college encounter a flesh-eating creature in the midst of its ritualistic eating spree.
Stranded on a lonely road, a bus full of high school basketball players, their coaches, and cheerleaders must defend themselves from the Creeper - a flesh-eating beast on the last day of his 23-day feeding frenzy. A farmer and his son set out on a personal mission to hunt the Creeper down.
On the last day of the Creeper’s 23-day feeding frenzy, the skeptical Sergeant Tubbs teams up with a task force hellbent on destroying the Creeper for good. The Creeper fights back in gory glory as its enemies grow closer than ever before to learning the secret of its dark origins.