Lam Hung is a loudmouth street hooker with a useless crippled gambling-addicted husband Ching and son Man. Hung's friend Fei is an nightclub hostess, and Fei's lesbian sister Mei/Mooi seems bent on total self destruction after her girlfriend May dumps her for a boy. Mei becomes mixed up with tabloid journalist Wah, who convinces her to allow him to photograph her as she jumps off a building. Hung receives a marriage proposal from regular client Wai, a police officer. Causing trouble for all of them is Saur, the local loan shark and crime boss. Ching is in debt to Saur, he runs the club where Fei works, and he brings in Mainland girls who undercut the local streetgirl's prices. Wah and Mei become sort-of lovers, and Wah does a story on the streetwalkers, in order to influence public opinion against Saur and his mainlanders.
元洲街王后红姐（吴家丽）感恩图报下嫁与阿正（张国强），并育有一子。正欲改善生活好让红姐能早日脱离苦海，奈何嗜赌加上残疾的影响反弄致负债累累，令红姐百上加斤。军装警察阿威（尹志强）心仪红姐多年，奈何红姐无法忍下心丢弃丈夫与儿子。红姐挚友，夜总会公开王妃（刘锦玲）为人有情有义，与细妹（刘玉翠）相依为命，但同性恋的细妹经常给她带来不少麻烦，令她烦恼不堪。 另方面，大佬文（成奎安）为在元洲街分得一杯羹，请来大批北妹杀入，令红姐等大受影响，而警方又不时放蛇捉客，令元洲街顿时变冷清清，大佬文迁怒于红姐，誓要把她赶尽杀绝，幸好危急关头时阿威赶致相救。
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