| Name | Type | Role |
|---|---|---|
| Wheein | Musical Guest | Mamamoo - Wheein |
| . | Musical Guest | Twice - Tzuyu |
| Shin Yu-na | Musical Guest | Itzy - Yuna |
| Jackson Wang | Musical Guest | Got7 - Jackson |
| Guan Yue | Musical Guest | Unine - Guan Yue |
| Kwon Soon-young | Musical Guest | Seventeen - Hoshi |
| Lucas Wong | Musical Guest | WayV - Lucas |
| Park Seong-hwa | Musical Guest | Ateez - Seonghwa |
| Lee Ho Joon | Musical Guest | Monsta X - Joohoney |
| . | Musical Guest | Twice - Jeongyeon |
| Kim Chung-ha | Musical Guest | Chungha |
| Choi Seung-cheol | Musical Guest | Seventeen - S.Coups |
| Hwang Ye-ji | Musical Guest | Itzy - Yeji |
| Boo Seung-kwan | Musical Guest | Seventeen - Seungkwan |
| Yeo Hwan-woong | Musical Guest | Oneus - Hwanwoong |
| Jung Woo-young | Musical Guest | Ateez - Wooyoung |
| Kim Tae-hyung | Musical Guest | BTS - V |
| Dua Lipa | Musical Guest | Dua Lipa |
| Kim Nam-joon | Musical Guest | BTS - RM |
| Choi Yeon-jun | Musical Guest | TXT - Yeonjun |
| Park Jin-young | Musical Guest | Got7 - Jinyoung |
| Jia Yi | Musical Guest | Unine - Jiayi |
| Jeon Won-woo | Musical Guest | Seventeen - Wonwoo |
| Xiao Dejun | Musical Guest | WayV - Xiaojun |
| Kim Hong-joong | Musical Guest | Ateez - Hongjoong |
| Im Chang Kyun | Musical Guest | Monsta X - I.M |
| . | Musical Guest | Twice - Momo |
| Sohn Hyun-woo | Musical Guest | Monsta X - Shownu |
| Yoon Jeong-han | Musical Guest | Seventeen - Jeonghan |
| Choi Ji-soo | Musical Guest | Itzy - Lia |
| Chwe Hansol Vernon | Musical Guest | Seventeen - Vernon |
| Son Dong-ju | Musical Guest | Oneus - Xion |
| Song Min-gi | Musical Guest | Ateez - Mingi |
| Jeon Jung-kook | Musical Guest | BTS - Jungkook |
| Lee Ji-hoon | Musical Guest | Seventeen - Woozi |
| Kim Young-jo | Musical Guest | Oneus - Ravn |
| Kim Seok-jin | Musical Guest | BTS - Jin |
| Choi Soo-bin | Musical Guest | TXT - Soobin |
| Im Jae-beom (JB) | Musical Guest | Got7 - JB |
| Hu Chunyang | Musical Guest | Unine - Chunyang |
| . | Musical Guest | Twice - Mina |
| Wong Kunhang | Musical Guest | WayV - Hendery |
| Li Wenhan | Musical Guest | Unine - Wenhan |
| Hwasa | Musical Guest | Mamamoo - Hwasa |
| Lee Min-hyuk | Musical Guest | Monsta X - Minhyuk |
| Hong Ji-soo | Musical Guest | Seventeen - Joshua |
| Shin Ryu-jin | Musical Guest | Itzy - Ryujin |
| Lee Chan | Musical Guest | Seventeen - Dino |
| Qian Kun | Musical Guest | WayV - Kun |
| Choi San | Musical Guest | Ateez - San |
| Xu Ming-hao | Musical Guest | Seventeen - The8 |
| Lee Seo-ho | Musical Guest | Oneus - Seoho |
| Min Yoon-gi | Musical Guest | BTS - Suga |
| Choi Beom-gyu | Musical Guest | TXT - Beomgyu |
| Choi Young-jae | Musical Guest | Got7 - Youngjae |
| Xia Hanyu | Musical Guest | Unine - Xia Hanyu |
| . | Musical Guest | Twice - Dahyun |
| Liu Yang Yang | Musical Guest | WayV - Yangyang |
| Li Zhenning | Musical Guest | Unine - Zhenning |
| Moonbyul | Musical Guest | Mamamoo - Moonbyul |
| Chittaphon Leechaiyapornkul | Musical Guest | WayV - Ten |
| Kang Yeo-sang | Musical Guest | Ateez - Yeosang |
| Yoo Ki-hyun | Musical Guest | Monsta X - Kihyun |
| Wen Jun-hui | Musical Guest | Seventeen - Jun |
| Lee Chae-ryeong | Musical Guest | Itzy - Chaeryeong |
| Park Jin-young | Musical Guest | J. Y. Park |
| Kang Tae-hyun | Musical Guest | TXT - Taehyun |
| BamBam Kunpimook Bhuwakul | Musical Guest | Got7 - BamBam |
| Chen You Wei | Musical Guest | Unine - Chen Youwei |
| Kim Min-gyu | Musical Guest | Seventeen - Mingyu |
| Kim Gun-hak | Musical Guest | Oneus - Leedo |
| Jung Ho-seok | Musical Guest | BTS - J-Hope |
| Solar | Musical Guest | Mamamoo - Solar |
| . | Musical Guest | Twice - Chaeyoung |
| Mark Tuan | Musical Guest | Got7 - Mark |
| Yao Mingming | Musical Guest | Unine - Mingming |
| Dong Sicheng | Musical Guest | WayV - Winwin |
| Jeong Yun-ho | Musical Guest | Ateez - Yunho |
| Im Na-yeon | Musical Guest | Twice-Nayeon |
| Chae Hyung-won | Musical Guest | Monsta X - Hyungwon |
| . | Musical Guest | Twice - Jihyo |
| Kai Kamal Huening | Musical Guest | TXT - Hueningkai |
| Kim Yu-gyeom | Musical Guest | Got7 - Yugyeom |
| He Changxi | Musical Guest | Unine - He Changxi |
| Lee Seok-min | Musical Guest | Seventeen - DK |
| Lee Keon-hee | Musical Guest | Oneus - Keonhee |
| Choi Jong-ho | Musical Guest | Ateez - Jongho |
| Park Ji-min | Musical Guest | BTS - Jimin |
| Park Bo-gum | Host | Main Host & presenter for Worldwide Fans' Choice |
| Guli Nazha | Guest Star | Presenter for Best Dance Solo Performance & Best Urban/Hip-Hop Music |
| Jung Hye-sung | Guest Star | Presenter for Best Male & Female Group |
| Joo Woo-jae | Guest Star | Presenter for Best Female Artist & Best New Asian Artist |
| Erika Karata | Guest Star | Presenter for Best New Male & Female Artist |
| Park Tam-hee | Guest Star | Presenter for Breakthrough Achievement Award |
| Kim Byung-hyun | Guest Star | Presenter for World Performer Award, Favorite Vocal Performance & Favorite Dance Performance |
| Kim Ji-sook | Guest Star | Presenter for Best Female Artist & Best New Asian Artist |
| Jimmy Fallon | Guest Star | Presenter for Album of the Year (Daesang) |
| Chang Chen | Guest Star | Presenter for Worldwide Icon of the Year (Daesang) |
| Yoon Jin-yi | Guest Star | Presenter for World Performer Award, Favorite Vocal Performance & Favorite Dance Performance |
| Lee Kwang-soo | Guest Star | Presenter for Worldwide Fans' Choice |
| Kentaro Sakaguchi | Guest Star | Presenter for Best Dance Performance – Male & Female Group |
| Cha Seung-won | Guest Star | Presenter for Song of the Year (Daesang) |
| Shin Ah-young | Guest Star | Presenter for Qoo10 Favorite Male & Female Artist |
| Choi Yu-hwa | Guest Star | Presenter for Worldwide Fans' Choice |
| Minatozaki Sana | Guest Star | Twice-Sana |
| Lee Sang-yeob | Guest Star | Presenter for Best Male & Female Group and Worldwide Fans' Choice |
| Saito Tsukasa | Guest Star | Presenter for Qoo10 Favorite Male & Female Artist |
| Shin Seung-hun | Guest Star | Presenter for Artist of the Year (Daesang) |
| Lee Soo-hyuk | Guest Star | Presenter for Best Dance Solo Performance & Best Urban/Hip-Hop Music |
| Lee Yoo-bi | Guest Star | Presenter for Worldwide Fans' Choice |
| Lee Yi-kyung | Guest Star | Presenter for Best New Male & Female Artist |
