Catherine Tate returns with her well-loved character Nan in her own sitcom for the BBC. While Jamie, Nan's grandson, is away in Africa doing voluntary work, a young girl called Alice has been allocated to Nan by the Young and Old Buddy-Up Foundation to keep her company and cheer her up. Alice soon discovers that Nan's kitchen tap is broken, and accompanies her to the council office to arrange to get it fixed. Unfortunately Nan, in her usual style, causes mayhem and upset at the offices, ending with her being given a community service order to work in the local hospital. Meanwhile Jamie, who is Skyping regularly from Africa, is concerned when he sees Nan in hospital, thinking she is seriously ill. At the same time, new neighbours have moved in across the corridor, and Nan gets involved in preparations for their family wedding party.