For all our advances in medical science, the number of people suffering from fertility issues remains stubbornly high. Across the UK, one in seven couples - around three and a half million people - will experience difficulty starting a family. Of those, a third have what is known as unexplained infertility - both partners are apparently fertile, and yet together cannot conceive a child. In this powerful documentary, we follow three couples as they each undergo a round of IVF treatment, in the hope of beating this maddening diagnosis. With frank testimony, we see what it’s really like to put your hopes of starting a family in the hands of the medical profession.