Jane Lynch hosts a group of actors who played doctors on television, including Torrey Devitto (Chicago Med), Dr. Dubrow (Botched), Ryan Eggold (New Amsterdam), Jason George (Grey's Anatomy), Hill Harper (The Good Doctor), Dr. Will Kirby (Dr. 90210), Dr. Sandra Lee (Dr. Pimple Popper), and Kal Penn (House). At the end of each trivia round, the contestants vote out who they perceive to be the weakest link, and Lynch sends them packing.