The roastmaster was Jeff Garlin. It featured performances and roasts by Jim Breuer, Mario Cantone, Lenny Clarke, Doctor Dre, Dane Cook, Nick DiPaolo, Adam Ferrara, Michael J. Fox, Peter Gallagher, Don Gavin, Gina Gershon, Gilbert Gottfried, Ed Lover, Joe Mantegna, Conan O'Brien, Colin Quinn, Rene Russo, Jon Stewart, and Christopher Walken.
| Name | Type | Role | |
|---|---|---|---|
| Denis Leary | Guest Star | ||
| Dane Cook | Guest Star | ||
| Adam Ferrara | Guest Star | ||
| Lenny Clarke | Guest Star | ||
| Mario Cantone | Guest Star | ||
| Elizabeth Hurley | Guest Star | ||
| John Fortenberry | Director |