Steven Avery is released after 18 years in prison, when evidence reveals he's innocent of a vicious attack on Penny Beerntsen. Within months he's arrested again, this time for the murder of a young lady. Can lightning strike twice? Or, did he do it?
When Viola Manville is beaten to death, police suspect Frank Sterling, whose brother Glen was convicted of an assault on Viola a few years earlier. Frank confesses to murder, and goes to prison. Until 18 years later, new evidence blows the case wide open.
DNA evidence is reexamined 14 years after Roger Coleman is executed for the murder of his sister-in-law, Wanda McCoy.
Kenny Waters is sentenced to life in prison for the fatal stabbing of his neighbor, Katharina Brow, but Kenny's sister, Betty Anne, is convinced of his innocence and works tirelessly to clear his name.
Six months after Melvin Ignatow is acquitted of murdering Brenda Schaefer, three rolls of undeveloped film are discovered under the floorboards in Ignatow's house which show what really happened.
When Toni Lister is found stabbed to death, there is insufficient evidence to charge either her husband, Calvin, or her husband's friend, Jimmy Eacker, then, 24 years later, DNA testing finally reveals the killer's identity.