| Name | First Aired | Runtime | Image | |
|---|---|---|---|---|
| S05E01 | Stewie Loves Lois | September 10, 2006 | 20 | |
| S05E02 | Mother Tucker | September 17, 2006 | 20 | |
| S05E03 | Hell Comes to Quahog | September 24, 2006 | 20 | |
| S05E04 | Saving Private Brian | November 5, 2006 | 20 | |
| S05E05 | Whistle While Your Wife Works | November 12, 2006 | 20 | |
| S05E06 | Prick Up Your Ears | November 19, 2006 | 20 | |
| S05E07 | Chick Cancer | November 26, 2006 | 20 | |
| S05E08 | Barely Legal | December 17, 2006 | 20 | |
| S05E09 | Road to Rupert | January 28, 2007 | 20 | |
| S05E10 | Peter's Two Dads | February 11, 2007 | 20 | |
| S05E11 | The Tan Aquatic With Steve Zissou | February 18, 2007 | 20 | |
| S05E12 | Airport '07 | March 4, 2007 | 20 | |
| S05E13 | Bill and Peter's Bogus Journey | March 11, 2007 | 20 | |
| S05E14 | No Meals On Wheels | March 25, 2007 | 20 | |
| S05E15 | Boys Do Cry | April 29, 2007 | 20 | |
| S05E16 | No Chris Left Behind | May 6, 2007 | 20 | |
| S05E17 | It Takes a Village Idiot... and I Married One | May 13, 2007 | 20 | |
| S05E18 | Meet the Quagmires | May 20, 2007 | 20 |
