| Name | First Aired | Runtime | Image | |
|---|---|---|---|---|
| S08E01 | Road to the Multiverse | September 27, 2009 | 20 | |
| S08E02 | Family Goy | October 4, 2009 | 20 | |
| S08E03 | Spies Reminiscent of Us | October 11, 2009 | 20 | |
| S08E04 | Brian's Got a Brand New Bag | November 8, 2009 | 20 | |
| S08E05 | Hannah Banana | November 8, 2009 | 20 | |
| S08E06 | Quagmire's Baby | November 15, 2009 | 20 | |
| S08E07 | Jerome is the New Black | November 22, 2009 | 20 | |
| S08E08 | Dog Gone | November 29, 2009 | 20 | |
| S08E09 | Business Guy | December 13, 2009 | 20 | |
| S08E10 | Big Man on Hippocampus | January 3, 2010 | 20 | |
| S08E11 | Dial Meg for Murder | January 31, 2010 | 20 | |
| S08E12 | Extra Large Medium | February 14, 2010 | 20 | |
| S08E13 | Go, Stewie, Go! | March 14, 2010 | 20 | |
| S08E14 | Peter-assment | March 21, 2010 | 20 | |
| S08E15 | Brian Griffin's House of Payne | March 28, 2010 | 20 | |
| S08E16 | April in Quahog | April 11, 2010 | 20 | |
| S08E17 | Brian & Stewie | May 2, 2010 | 20 | |
| S08E18 | Quagmire's Dad | May 9, 2010 | 20 | |
| S08E19 | The Splendid Source | May 16, 2010 | 20 | |
| S08E20 | Something, Something, Something, Dark Side | May 23, 2010 | 20 | |
| S08E21 | Partial Terms of Endearment | June 20, 2010 | 20 |
