Princess Glama of the planet Camelotta is kidnapped by Zangra and her robot henchman Drako, who use her as bait to trap the Goof-ups; however, the heroes prove to be so incompetent that the villains have to help them get into the trap. Once inside, the Goof-ups' bungling enables them to rescue the princess and escape.
General Blowhard is carrying secret plans to prevent the Space Spider's plot to take over the universe. The General needs a good night's sleep before the next day's high-level meeting, so the Goof-ups have to capture the Space Spider and protect the General without waking him up.
Sagar the hunter, with the aid of his lackey Grog, has been capturing "lower life-forms" for an interplanetary zoo, and he plans to add the Galaxy Goof-ups—the lowest life-forms he's ever seen—to his collection. After being lured into Sagar's trap, the heroes and Captain Snerdley try to escape, accidentally releasing all the other animals in the process.
The Goof-ups are assigned to deliver a shipment of gold bullion from the Galaxy Bank to the Galaxy Mint, but they're tricked into handing it all to Captain Sly and his space pirates, so they have to get it back.
Tacky Cat is seeking revenge against Captain Snerdley for kicking him out of the service. To this end, he steals a cloning machine from Command Central, and kidnaps Snerdley because no one else knows how to operate
Command Central receives a shipment of the latest top-secret equipment. Zangra, disguised as interviewer Barbie Wally (a take-off of Barbara Walters), tricks the Goof-ups into loading all the equipment onto her ship. However, they accidentally take off in her ship, so Zangra and Drako go after them in the Goof-ups' ship.
Tacky Cat—under orders from his wife Perfecta, who hates the tacky way they live—takes over the planet Camelotta and imprisons Princess Glama. The Goof-ups arrive to free the princess, and Perfecta's constant nagging drives Tacky Cat to surrender to them. In the end, however, Glama comes up with a solution to the Cats' marital discord: she has their planet made half-pristine and half-tacky, so they can both be happy.
The vessel Space Station USA, which had been missing for centuries, is found floating in space; Captain Snerdley orders the Goof-ups to pilot the station to the Galaxonian Museum. The richest man in the galaxy, however, wants to add the vessel to his own collection (which appears to include the Starship Enterprise), so he uses disguises and trickery to steal it from the Goof-ups. During this episode, the Goof-ups encounter four female versions of themselves, and accompany them to the disco.
A jungle-covered planet has drifted into Command Central's galaxy, and the Goof-ups are sent to investigate it. The primitive natives are so impressed with Yogi's "magic"—i.e., his hand-held teleportation device—that the tribe's queen makes him their new witch doctor, and he and his crewmates live a life of luxury. However, when Yogi realizes that the queen intends to marry him, he and his friends desperately try to escape from the planet. In this episode, the Goof-ups don't go to a disco; instead, they dance to music from a radio while on the jungle planet.
Dyno-Mite, a tiny space villain, causes chaos when he steals a new weapon, the Stretch-Shrink Ray.
The vampire Count Vampula plans to take over the universe with his army of zombies. The first step in his plan is to put the bite on Captain Snerdley, turning him into the Count's vampire slave, so that the Galaxy Goof-ups will be lured into a trap and turned into vampires as well.
Rupert and Dimitri (spoofs of Sydney Greenstreet and Peter Lorre) deliberately cause a remote-controlled ship to crash down on the jungle planet Congo-Bongo; this ship carries the treasure-matic computer, which can produce precious metals and gems. The villains then race the Goof-ups through the perils of the jungle to get the computer.
The General sends Captain Snerdley to the Galaxy Sanitarium for his overworked nerves; visits from the Goof-ups make his condition even worse. Meanwhile, the reptilian Lozar from the planet Lizardia uses the body of head psychiatrist Dr. Wacceau as a disguise, so he can study Snerdley's mind and body; once the study is complete, the Lizardian invasion will begin.
