The Season 4 finale sees big bets and big bluffs backfire for Daniel Negreanu as Antonio Esfandiari, Sammy Farha, David Benyamine, Patrik Antonius, Guy Laliberte, Barry Greenstein, and Doyle Brunson conclude the season on High Stakes Poker.
| Name | Type | Role | |
|---|---|---|---|
| Gabe Kaplan | Host | Himself - Commentator | |
| A.J. Benza | Host | Himself - Commentator | |
| Patrik Antonius | Guest Star | ||
| Antonio Esfandiari | Guest Star | ||
| Guy Laliberté | Guest Star | ||
| Sam Farha | Guest Star | ||
| Daniel Negreanu | Guest Star | ||
| David Benyamine | Guest Star | ||
| Doyle Brunson | Guest Star | ||
| Barry Greenstein | Guest Star |