In 2003, a new infectious disease (SARS) spread across Asia. Shi-Kai Lo and Yumei Chen are doctors from Taipei Bo-Ai Hospital. Under the leadership of the latest director, Bo-Ai Hospital turns into a profit oriented business model, which goes against the doctors' initial intent to save people. But after Shi-Kai Lo fails to be promoted as the vice director of the hospital, he quits in a feat of rage. He then remembers the director's proposal to transfer him to being an official at the Department of Health of Taipei.