In 1996, detectives were called to a road rage stabbing that saw Stephen Cameron die from his injuries, launching a hunt for notorious criminal Kenneth Noye.
After a family wedding, an 18-year-old is found tied to a pole and her family murdered. Detectives pursue escaped rapist Arthur Hutchinson, in a tense two-week manhunt.
In 2011, a spate of unexplained hospital deaths in northern England triggers a police hunt for a serial killer, with evidence pointing to one man - Victorino Chua.
In 2015, Amanda Taylor brutally murdered her father-in-law and took a selfie with the body. On the run and posting online, police raced to stop her before she killed again.
In 2012, 18-year-old Samantha Koenig vanished from her coffee kiosk. Investigators trace her abductor, Israel Keyes, whose crimes and confessions leave detectives stunned.
In 2014, two Pennsylvania troopers are shot by sniper Eric Frein, who evades capture for 48 days. Police launch a manhunt across rugged terrain to bring him to justice.
After 17-year-old Shari Smith is abducted, sadistic killer Larry Gene Bell begins calling the family to taunt them. As another girl is taken nearby, detectives race to catch him.