Dave welcomes actor Michael J. Fox, a Top Ten List presented by Ashton Kutcher, Jon Cryer and Angus T. Jones from the CBS comedy series "Two and a Half Men", comedian Jim McDonald and musical guest John Doe.
| Name | Type | Role | |
|---|---|---|---|
| Michael J. Fox | Guest Star | ||
| Jim McDonald | Guest Star | ||
| John Doe | Guest Star |