In the aftermath of The Avengers' battle in New York City, the world attempts to come to grips with the presence of superheroes, gods, and aliens in their midst. Agent Coulson is resurrected under mysterious circumstances and forms an elite team of agents from S.H.I.E.L.D. to keep track of a secret organization known as The Rising Tide. Meanwhile, they must deal with other menaces, such as a man who suddenly finds himself with vast uncontrollable power.
Dark secrets are revealed as Coulson and his team put everything on the line to stop Garrett and the forces of Hydra. But when the dust settles, Coulson will find that no one’s leaving this battle unscathed. And just when all hope seems lost, they’re joined by the one man who may be able to turn the tide–Nick Fury.
In light of the Sokovia Accords, and with Hydra obliterated, S.H.I.E.L.D. has been legitimatized again and no longer needs to operate in the shadows. Since the world presumes that Coulson is dead, the organization needed a new Director to be the face of the organization. Coulson finds himself back in the role as an agent and teamed with Mack, and together they are tasked with tracking down and confirming the presence of Enhanced people, aka Inhumans. Agent May is tasked with training specialist strike teams, and Fitz and Simmons have taken a big step forward in their relationship.
Following Coulson's stepping down as Director, Jeffrey Mace is made the new Director of S.H.I.E.L.D. and its public face. Daisy meets with Robbie at his place of work, saying she knows about his history but is surprised to find he isn't Inhuman like her. May's exposure from the specter last episode gets out of hand where Mace, revealing he's a super strong Inhuman, knocks her out and sends her to an undisclosed location. Mack & Fitz investigate the specter and encounter Ghost Rider. The specter who infected May releases her compatriots who were in similar containers for years due to using the "Darkhold".