任職藥廠的程琛（苗僑偉飾）一直奉行“阿Q精神”來應付家中的強人老婆高勵心（張可頤飾）高壓折磨， 因為婚後七年來他一直被老婆誤會為大滾友，以致他的一舉一動日夜備受老婆嚴密監控；對於他的遭遇， 親弟情場浪子的程義（謝天華飾）雖表同情卻經常取笑程琛，更不時作其軍師教路；一日，程琛在深圳被老婆發現有姦情， 她憤然提出離婚……另一方面，程義自詡情場未逢敵手，卻偏偏敵不過新加入藥廠的高層繆靈芝（李綺虹飾）的誘惑， 幾乎害自己成了事業及感情上的雙失酷男…… 愛情火花可以轟轟烈烈，婚姻生活卻流於雞毛蒜皮？苗僑偉全新「戲」勢，演繹弱勢小男人；張可頤久休復出第一激， 激惡演繹吃醋大女人；時裝喜劇《老公萬歲》以幽默諷刺的手法反映現代兩性熱門話題，笑位連場！
| Season | From | To | Episodes |
|---|---|---|---|
| All Seasons | |||
| Specials | 0 | ||
| Season 1 | February 2010 | March 2010 | 22 |
| Unassigned Episodes | 0 |
| Season | From | To | Episodes |
|---|---|---|---|
| Unassigned Episodes | 22 |
| Season | From | To | Episodes |
|---|---|---|---|
| Season 1 | 0 | ||
| Unassigned Episodes | 22 |
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