Cicely's newest resident, Mike Monroe, is confined to live in a plastic bubble because of M.C.S. (Multiple Chemical Sensitivity), which makes him allergic to nearly everything manufactured in the twentieth century. After Maggie meets Mike she becomes interested in him. Ruth-Anne's son Matthew, the investment banker, comes to Cicely to try to get away from it all when he is fired from his job. Maurice's prospectus on making Cicely a place for sick people to move to and recover from their illnesses draws Matthew back into thinking about money.
| Name | Type | Role | |
|---|---|---|---|
| Mark B. Perry | Writer | ||
| Joe Lazarov | Producer | Associate Producer | |
| Jeff Melvoin | Producer | Supervising Producer | |
| Diane Frolov | Producer | Supervising Producer | |
| Michael Vittes | Producer | Supervising Producer | |
| Martin Bruestle | Producer | Co-Producer | |
| Geoffrey Neigher | Producer | Co-Producer | |
| Robin Green | Producer | Supervising Producer | |
| Joel Polis | Guest Star | Matthew Miller | |
| Anthony Edwards | Guest Star | Mike Monroe | |
| Rob Thompson | Executive Producer | Co-Executive Producer | |
| Joshua Brand | Executive Producer | Executive Producer | |
| John Falsey | Executive Producer | Executive Producer | |
| Andrew Schneider | Executive Producer | Co-Executive Producer | |
| Rob Thompson | Director | ||
| Frank Prinzi | Crew | Director of Photography | |
| David Schwartz | Crew | Music | |
| Elaine Miles | Actor | Marilyn Whirlwind | |
| John Cullum | Actor | Holling Vincoeur | |
| Peg Phillips | Actor | Ruth-Anne Miller | |
| Darren E. Burrows | Actor | Ed Chigliak | |
| Rob Morrow | Actor | Dr. Joel Fleischman | |
| John Corbett | Actor | Chris Stevens | |
| Barry Corbin | Actor | Maurice J. Minnifield | |
| Cynthia Geary | Actor | Shelly Marie Tambo | |
| Janine Turner | Actor | Maggie O'Connell |