The cast travels to California and adjusts to their new jobs, a new city, and each other. Heather and Fernando have to deal with not working while they wait on getting their RN licenses approved, and Adrian tries to cope with missing his ex-girlfriend. Tyrice and Chris butt heads over a misunderstanding and Tyrice takes her anger out on Adrian when he tries to stay neutral in the argument.
Tyrice feels alone and considers quitting, Fernando makes a mistake after a night of partying, and Heather's boyfriend Dalton comes to visit.
Crystal struggles with trust issues, Nikki has a makeover, the group goes to an island, and everyone struggles to tolerate Chris.
Heather spends more time with Adrian despite her engagement to Dalton. Chris finds himself growing further apart from the group. He is pushed to the brink during a fight with Fernando and threatens to leave for good.
Chris starts dating a girl who works with him at the hospital. A confrontation erupts between Tyrice and the other girls and quickly gets out of hand.
Tyrice throws a birthday bash and things get heated when it seems that Heather and Adrian finally cross the line and head home together.
The group questions what really went on between Adrian and Heather. Chris risks heartbreak when he confesses his true feelings to his visiting friend Natalie.
The group heads to Palm Springs for some R&R but all hell breaks loose between them. Heather, Tyrice, Adrian and Chris try to salvage the trip by going skinny-dipping together.
The nurses return from their Palm Springs debacle and relationships continue to unravel. With the end of their assignment nearing, everyone is trying to figure out his or her next move.
After hashing it out with Heather, Dalton confronts Adrian about crossing the line with his fiance. Heather is forced to decide whether she is going to stick with Dalton, or admit her true feelings to Adrian.