College student Alyssa looks forward to her senior year so she can finally hold her head up high, date a guy and have a "real" college experience after being born with a disabling genetic disorder that affected her smile. Baseball lover Mark plays a high stakes game to get the smile he has always wanted. After struggling with drug addiction, Mark is clean and sober--but will his massive dental surgery force him back on pain medication and jeopardize his sobriety?
An aspiring beautician tries to overcome her extreme fear of dentists; an actress confronts years of shame over her rotting teeth.
A woman who neglected her teeth for years while she helped raise her nine siblings receives dental care; a stay-at-home mom wants to return to the workforce but fears she looks like a witch, due to her teeth.
Jacqueline looks to find closure from the brutal attack that stole her smile and almost cost her life. Single mom Crissy wants to step out of the shadows and teach her daughters how to live a life filled with self-esteem.
Nigel's life and mouth went off the rails when his front tooth was knocked out while Julie's teeth are a "horror show" that have derailed her life and kept her daughter from leaving home.
Sarah wants to start a family with her husband but the infection coursing through her body stops her in her tracks. Chris has always wanted to take care of the problem that has haunted him but instead he puts his family first.