After 21 years of entertainment combined with campaigning consumer journalism, That's Life! comes to an end with this, its 418th edition. Esther Rantzen is joined for this nostalgic celebration by all the presenters featured over the years, along with Wet Wet Wet, whose 1988 version of With a Little Help from My Friends raised more than £100,000 for Childline, and Victoria Wood , who reflects on her regular appearances back in 1976. Remember Prince, the dog who loved "sausages"? Or the time Esther was arrested handing out bat stew on a London street? And That's Life's Jobsworth award (to petty-minded officialdom) has ensured the word an established place in the English language. Some of the campaigns have led to changes in the law and there are many stories of courage and hope - including the organ-transplant fund that started with 2-year-old Ben Hardwick in 1984. Ten years on his mother Debbie is in the studio to talk about Ben's life.