Celebrity guests for 2022 are Stephen Merchant, Katherine Ryan, Richard Ayoade, Maisie Adam, Jonathan Ross and Rose Matafeo. As always, Jimmy will be ably assisted by a panel of top celebrity teams and a series of superstar question setters including Mitchell Brook Primary School and Charles Dance.
| Name | Type | Role | |
|---|---|---|---|
| Charlie Skelton | Writer | ||
| Dominic English | Writer | ||
| James Farmer | Writer | ||
| Christine Rose | Writer | ||
| Shaun Pye | Writer | ||
| Jimmy Carr | Writer | ||
| Johannes Radebe | Guest Star | ||
| Jonathan Ross | Guest Star | ||
| Charles Dance | Guest Star | ||
| Maisie Adam | Guest Star | ||
| Jerry Dyer | Guest Star | ||
| Richard Ayoade | Guest Star | ||
| Katherine Ryan | Guest Star | ||
| Subwoolfer | Guest Star | ||
| Stephen Merchant | Guest Star | ||
| Millie Bright | Guest Star | ||
| Rose Matafeo | Guest Star | ||
| Mick Thomas | Director |