Sawada Takuto struggles to find a job as he nears the end of his college years. At a job interview, he meets Hongo Megumi, a classmate who is bearing similar pressures.
Slowly realizing his body is acting up, Takuto feels useless at his new full-time job. Megumi continues to job hunt and soul search, when suddenly Takuto's friend, Shigeyuki, offers to help her.
Takuto and Megumi go on a romantic getaway after Takuto learns he has ALS.
After learning about Megumi's background, Takuto has to decide once and for all whether or not to tell Megumi about his disease.
Takuto lets a few people know about his illness. Meanwhile, Megumi and Shigeyuki's relationship continues to progress.
Takuto adapts to life in a wheelchair as Rikuto unravels and opens up to his brother.
Takuto is left living at home by himself after Rikuto moves back in with his parents. Mamoru confronts Megumi about the situation and asks if she can help.
Megumi strengthens her resolve, while Takuto questions his words and actions.
Both Takuto and Rikuto discover new goals, as Megumi faces opposition from her mother about her decision to stay by Takuto's side instead of marrying Shigeuki.
Takuto and Megumi take a walk down memory lane, as Takuto faces the most difficult decision he will ever have to make.
Takuto speaks at a school in front of his loved ones and peers about what ALS has taught him about life.
Are You Sure?