Jonathan is joined this time by Liam Gallagher, John Squire, the record-breaking RAYE, Stranger Things star Millie Bobby Brown, Rob Beckett and darts star Luke 'The Nuke' Littler.
| Name | Type | Role | |
|---|---|---|---|
| Jonathan Ross | Writer | ||
| James Farmer | Writer | ||
| Annie McGrath | Writer | ||
| Liam Gallagher | Musical Guest | ||
| RAYE | Musical Guest | ||
| John Squire | Musical Guest | ||
| Millie Bobby Brown | Guest Star | ||
| Luke Littler | Guest Star | ||
| Rob Beckett | Guest Star | ||
| Chris Howe | Director |