Dr. Venture, Pete White and Master Billy Quizboy are invited to take part in a top secret government think tank run by supergenius Professor Impossible (coincidentally their former college professor), but Doc's life is in jeopardy once he learns the dark secrets of Impossible's sequestered family. Meanwhile, Hank has become a walking time bomb thanks to a stolen Cold War serum, and Brock and Dean must race the clock to save him.
| Name | Type | Role | |
|---|---|---|---|
| Jackson Publick | Writer | ||
| Stephen Colbert | Guest Star | ||
| Doc Hammer | Guest Star | ||
| Mia Barron | Guest Star | ||
| Christopher McCulloch | Guest Star | ||
| Jackson Publick | Director |