Can Dr Una reverse the effects of 20 years of physical and mental neglect for 40-year-old Jo Mayne? Jo is a visiting officer for the local council. Not only is the job stressful, so is spending so much time on the road. Come Friday night, her stress levels are so high that she does what many people do, and drinks herself into oblivion. She also smokes heavily, and admits to using most feelings - happy, sad, stressed, bored - as an excuse for a cigarette.