El Señor Plácido López Turruviates, su esposa Renata y sus dos hijos, Plutarco y Martina, viven muy felices en un pequeño apartamento en la Colonia de los doctores de la Ciudad de México, pero hace un año el abuelo López, padre de Placido, se muda a vivir con ellos ya que no tiene más a donde ir. Cinco años antes de la llegada del abuelo Arnoldo, llega la Tía Licha y su hija a la que llaman La Nena pues su nombre no ha sido mencionado a lo largo de la serie, pues ambas fueron abandonadas por su marido, luego de que éste se "destapara" como homosexual.
| Season | From | To | Episodes |
|---|---|---|---|
| All Seasons | |||
| Specials | 0 | ||
| Season 1 | March 2007 | September 2007 | 24 |
| Season 2 | August 2019 | October 2019 | 13 |
| Season 3 | October 2019 | November 2019 | 13 |
| Season 4 | August 2020 | October 2020 | 13 |
| Season 5 | October 2020 | November 2020 | 13 |
| Season 6 | September 2021 | October 2021 | 15 |
| Season 7 | October 2021 | December 2021 | 15 |
| Season 8 | September 2022 | October 2022 | 15 |
| Season 9 | October 2022 | December 2022 | 15 |
| Season 10 | September 2023 | November 2023 | 16 |
| Season 11 | August 2024 | 15 | |
| Season 12 | August 2025 | 14 | |
| Unassigned Episodes | 0 |
| Season | From | To | Episodes |
|---|---|---|---|
| Specials | 0 | ||
| Unassigned Episodes | 181 |
| Season | From | To | Episodes |
|---|---|---|---|
| Season 1 | 0 | ||
| Unassigned Episodes | 181 |
| Name | Number of Episodes | Dates | |
|---|---|---|---|
| Jorge Ortiz de Pinedo | N/A |
| Name | Number of Episodes | Dates | |
|---|---|---|---|
| Luis Bautista | N/A |
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