Hendrik le Roux is sentenced to three years in prison for fraud. It doesn't take long to realise that the world inside prison is every bit as corrupt as the world outside. How long will he be able to withstand the pressures and scheming of gang leaders Priester and Pappa, arch-scoundrel Skollie and backstabbing Polka?
There’s great excitement about the annual boxing tournament, which presents inmates with the perfect opportunity for all sorts of smuggling activities. When his plotting with Tiger goes wrong, Pappa is furious.
Tiger and Skollie are planning an escape. They come across a stash of dagga in a steel pipe. Pappa and Priester put Polka under pressure to find the missing drugs. They suspect Le Roux and decide to teach him a lesson: first he gets assaulted in the shower, then a file is planted in his cell.
After their escape, Tiger and Skollie hide out at Tiger’s wife’s house. Meanwhile, Polka is under pressure from Priester and Pappa to find out where the two escaped men are.
It seems that Polka’s trap for Gerrie Prinsloo is working. Skollie and Tiger realise that the outcome of the boxing match, as well as the disappearance of Polka and Pappa’s dagga, have created lots of trouble for them.
Skollie is trying to find out who revealed their hiding place to the police. Hendrik le Roux’s wife is worried about his state of mind. Tiger escapes from hospital.
Tiger hides with Skollie’s brother, and Skollie escapes again.
Finale. The head of the prison is furious about Skollie’s escape and after a wild chase, Tiger and Skollie are brought back to prison once again. Hendrik, Priester and Polka also try to escape, but Hendrik surrenders and Polka is captured.
"Skollie" a popular South African jail bird hears his son is being abused. He gets an opportunity to break free and meets a friend outside but the friend uses the opportunity to abuse him while running from the law.
Former prison guard Gerrie Prinsloo is sentenced to two years in prison for accepting a bribe from Polka. It seems that Spyker Malan knows a lot more about Pappa than Pappa would like. Skollie is obsessed with seeing his son, but has no idea what the boy’s surname is. Henrik le Roux fears his release.
Skollie believes that his son is coming to visit him and tries to sort out a few gifts. He’s also planning a “Comrades marathon” and wastes no time in recruiting Hendrik and Gerrie for his team. Bets for the event cause a confrontation between Pappa and Priester. Meanwhile, Roelof is planning his third escape to earn his so-called “Springbok status”.
Freek and Frik are planning to escape during the Comrades and Spyker is drawn into their plans. The special cake for the Comrades winning team land in the wrong hands and almost cause a war.
Wrestler Big Bull arrives in prison and Skollie wastes no time in trying to gain from the situation. Prison cook Ertjies get rejected by Pappa and his gang, which leads to a hostage situation. Hendrik becomes a target for Priester’s dagga smuggling.
Exam papers are stolen from Prof’s cell and sold to the inmates. Skollie is once again preparing himself for a possible visit from his son. Hendrik discovers that his wife is having an affair. Priester and Skollie are planning a wrestling match between Big Bull and Punkie – with disastrous consequences for Skollie.
Finale. Hendrik escapes and the prison head has to act quickly to prevent a family murder. Priester’s plans to smuggle Gabba out of prison are thwarted. Skollie’s past is revealed, with surprising consequences.
Vyfster: Die Slot follows Skollie's battle to find his son despite the scheming of his enemies inside and outside prison.