In Dec 2000, 21-year-old Barry was sentenced to life in prison for murdering his girlfriend, his time in jail saw him beaten and succumb to a devastating drug addiction.
Louise and the team prove that the evidence is flawed, and the conviction is quashed. Yet it would be 13 years after the murder before her real killer is brought to justice.
In December 2010, Joanna Yeates was found dead in the snow near her home. Within hours her landlord Christopher Jefferies would find himself arrested on suspicion of murder.
Mr. Jeffries was released on bail after three days, but he would still be the subject of continued speculation and hounding by the police and the press for another two months.
Timothy Evans was hanged for murdering his wife and their baby daughter. Star witness for the prosecution was his landlord, John Christie of 10 Rillington Place.
With Evans hanged for a crime he did not commit, the local death toll of women was increasing - justice would eventually catch up with John Christie.
Colin Stagg is imprisoned for the murder of Rachel Nickel
The murder trial against Colin Stagg collapses, but it would be 16 years before a breakthrough in DNA evidence would catch the real killer, Robert Napper.
In October 1975, schoolgirl Lesley Molseed went missing, and within days Stefan Kiszko was arrested and charged with her murder
Forensic evidence proved that Kiszko could never have committed the murder, and it would be 32 years later that the real killer would be convicted.