 
     
        The season, which takes place fourteen years after the ninth season (2001–02) and seven years after the film The X-Files: I Want to Believe (2008), follows newly re-instated Federal Bureau of Investigation (FBI) agents Fox Mulder (David Duchovny) and Dana Scully (Gillian Anderson) as they learn more about the existence of extraterrestrials and their relationship with the government.
| Name | First Aired | Runtime | Image | |
|---|---|---|---|---|
| S10E01 | My Struggle | January 24, 2016 FOX | 45 | |
| S10E02 | Founder's Mutation | January 25, 2016 FOX | 45 | |
| S10E03 | Mulder & Scully Meet the Were-Monster | February 1, 2016 FOX | 45 | |
| S10E04 | Home Again | February 8, 2016 FOX | 45 | |
| S10E05 | Babylon | February 15, 2016 FOX | 45 | |
| S10E06 | My Struggle II season finale | February 22, 2016 FOX | 45 |