Getting back on his feet after the Ku Zu Ryu Sen, Shishio gets ready to use the final and ultimate Secret Sword attack, the Kaguzuchi. Kenshin also prepares to use his ultimate move, the Amakakeru Ryu no Hirameki. The blades end up hitting each other and the attack does not connect properly. However, Kenshin's attack created a vacuum utilizing the Amakakeru Ryu no Hirameki and the Kaguzuchi's sheer power, and temporariliy immobilized Shishio. Not missing this chance, Kenshin strikes Shishio with an immensely strong consecutive hit. Shishio miraculously stands back up, but since he has fought far longer than fifteen minutes, his blood starts evaporating and he begins screaming in pain. In utter fear of Shishio's death, Yumi rushes over by Shishio, and begs Kenshin not to finish him off. However, Shishio stabs Kenshin through Yumi! He is determined to continue fighting, and Yumi dies happily, knowing she did something useful for once. As the battle continues, the battle is once again at a standstill. Then suddenly, the scorching heat in Shishio's body causes him to end up being burned alive once again, this time fatally. Houji, refusing to accept Shishio's defeat, maniacally attempts to destroy the Inferno Arena to take out Sanosuke, Kenshin, Saito, and Aoshi.
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